Publications

Siyuan Wang, Jun-Han Su, Brian J. Beliveau, Bogdan Bintu, Jeffrey R. Moffitt, Chao-ting Wu & Xiaowei Zhuang, Spatial organization of chromatin domains and compartments in single chromosomes, Science, Volume 353, Issue 6299, Pages 598-602, DOI: 10.1126/science.aaf8084, (2016). (Link) Highlighted in F1000Prime.

Mengwei Hu & Siyuan Wang, Chromatin tracing: Imaging 3D genome and nucleome, Trends in Cell Biology, Volume 31, Issue 1, Pages 5-8, (2020). (Link)
Selected as Best of 2021: Trends in Cell Biology. (Link)

Miao Liu*, Yanfang Lu*, Bing Yang, Yanbo Chen, Jonathan S.D. Radda, Mengwei Hu, Samuel G. Katz & Siyuan Wang, Multiplexed imaging of nucleome architectures in single cells of mammalian tissue, Nature Communications, Volume 11, Number 2907, (2020). *Co-first authors. (Link)
Featured by BioArt.

Mengwei Hu*, Bing Yang*, Yubao Cheng, Jonathan S.D. Radda, Yanbo Chen, Miao Liu & Siyuan Wang, ProbeDealer is a convenient tool for designing probes for highly multiplexed fluorescence in situ hybridization, Scientific Reports, Volume 10, Number 22031, (2020). *Co-first authors. (Link).

Ahilya N. Sawh, Maxwell E.R. Shafer, Jun-Han Su, Xiaowei Zhuang,  Siyuan Wang & Susan E. Mango, Lamina-Dependent Stretching and Unconventional Chromosome Compartments in Early C. elegans Embryos, Molecular Cell, Volume 78, Issue 1, Pages 96-111, (2020). (Link)

Yubao Cheng*, Miao Liu*, Mengwei Hu & Siyuan Wang, TAD-like single-cell domain structures exist on both active and inactive X chromosomes and persist under epigenetic perturbations, Genome Biology, Volume 22, Number 309, (2021). *Co-first authors. (Link).

Liana Boraas*, Mengwei Hu*, Lauren Thornton, Charles E. Vejnar, Gang Zhen, Antonio J. Giraldez, Christine Mayr, Siyuan Wang# & Stefania Nicoli#, Non-coding function for mRNAs in focal adhesion architecture and mechanotransduction, bioRXiv, doi: https://doi.org/10.1101/2021.10.04.463097, (2021).  *Co-first authors. #Co-corresponding authors. (Link).

Miao Liu, Bing Yang, Mengwei Hu, Jonathan S.D. Radda, Yanbo Chen, Shengyan Jin, Yubao Cheng & Siyuan Wang, Chromatin tracing and multiplexed imaging of nucleome architectures (MINA) and RNAs in single mammalian cells and tissue, Nature Protocols, Volume 16, Pages 2667-2697 (2021). (Link).

Yanfang Lu*, Miao Liu*, Jennifer Yang, Sherman M. Weissman, Xinghua Pan#, Samuel G. Katz#, & Siyuan Wang#, Spatial transcriptome profiling by MERFISH reveals fetal liver hematopoietic stem cell niche architecture, Cell Discovery, Volume 7, Number 47 (2021). *Co-first authors. #Co-corresponding authors. (Link)
Featured by Genetic Engineering & Biotechnology News (GEN). (Link)